Peptides EP06817_1 | HPV 16/18 E7 11-19 (HLA-A*02:01)

品名：HPV 16/18 E7 11-19 (HLA-A*02:01)

货号：EP06817_1

规格：1 mg; 5 mg

品牌：Peptides.de

产品描述

YMLDLQPET is a linear peptide epitope corresponding to residues 11 through 19 of the E7 oncoprotein from Human papillomavirus type 16 (HPV-16, UniProt: P03129) and HPV-18 (UniProt: P06788). Classified under epitope ID 75074, this sequence is associated with the Alphapapillomavirus 9 and Alphapapillomavirus 7 species groups, respectively. This HLA-A*02:01-restricted epitope has been extensively characterized for its immunological relevance, including its capacity to be recognized by both CD8⁺ T cells and B cells. It has been tested in T cell functional assays, B cell reactivity assays, and MHC class I ligand binding studies, highlighting its value in HPV-specific immune monitoring and vaccine development. The E7 protein itself plays a central role in HPV-driven oncogenesis. It interferes with host immune responses, making E7-derived epitopes such as YMLDLQPET particularly important in the context of cancer immunotherapy research. This peptide is frequently used in experimental settings involving antigen presentation, cytotoxic T lymphocyte responses, and the evaluation of HPV-targeted immunotherapeutic strategies.