Peptides EP07741_1 | HPV 16/18 E7 49-57 (H-2 Db)

品名：HPV 16/18 E7 49-57 (H-2 Db)

货号：EP07741_1

规格：1 mg; 5 mg

品牌：Peptides.de

产品描述

RAHYNIVTF is a well-characterized linear epitope derived from residues 49 to 57 of the E7 oncoprotein of Human papillomavirus type 16 (HPV-16, UniProt: P03129), as well as the homologous sequence from HPV-18 (UniProt: P06788). This H-2 Db-restricted peptide is catalogued under epitope ID 53112. Widely recognized for its robust immunogenicity in murine models, RAHYNIVTF has been investigated in over a hundred scientific publications. It has been tested in T cell assays, especially, but also in B cell assay and MHC ligand binding assays. Its widespread use in immunological studies makes it one of the most thoroughly validated HPV E7 epitopes available. This peptide has been evaluated across a diverse range of functional T cell assays, including: Cytotoxicity and T cell activation   TNF-α, IL-2, IL-4, IL-10, TGF-β, and granzyme B release   Proliferation and degranulation assays   Pathogen and tumor burden post-challenge   Survival outcomes in viral or tumor models   Adoptive transfer and protection assays   Due to its proven utility in preclinical tumor models and viral immunity research, RAHYNIVTF serves as a key tool for studying antigen-specific CD8⁺ T cell responses in the context of HPV-related cancer immunotherapy and vaccine development. This peptide is in stock and available for immediate delivery.