Peptides EP14274_1 | IE62 593-601 (HLA-A*02:01)

品名：IE62 593-601 (HLA-A*02:01)

货号：EP14274_1

规格：1 mg; 5 mg

品牌：Peptides.de

产品描述

IE62 593-601 (HLA-A*02:01) is a linear peptidic epitope with the amino acid sequence ALWALPHAA, studied as part of Major viral transcription factor ICP4 homolog from Human herpesvirus 3/Varicella-zoster virus. This epitope has been studied for immune reactivity and has been tested in T cell assays. The Major viral transcription factor ICP4 homolog is the most important transactivator of the Varicella zoster virus and therefore essential for its growth. [1] IE62 comprises 1,310 amino acids and is also known as VZV immediate early 62 protein (IE62). Upon infection, this tegument protein is introduced into the nuclei of host cells, where it acts as a transcriptional transactivator: It initiates the replication of the varicella zoster virus by transactivating viral immediate early, early and late genes. IE62 interacts with components of the host cell's transcription apparatus and recruits them to viral promoters. The link to the full publication can be found under the References tab.Read more about the Varicella zoster virus and its proteins in our blog post: "Varicella Zoster Virus: gE, IE-62 and IE-63 essential for Infection"