Peptides EP11314_1 | Influenza A M1 13-21 (HLA-A*11:01)(HLA-A*03:01)(HLA-A*31:01)(HLA-A*68:01)

品名：Influenza A M1 13-21 (HLA-A*11:01)(HLA-A*03:01)(HLA-A*31:01)(HLA-A*68:01)

货号：EP11314_1

规格：1 mg; 5 mg

品牌：Peptides.de

产品描述

The Influenza A M1 13–21 epitope (amino acid sequence: SIIPSGPLK) is a well-characterized CD8⁺ T cell epitope derived from the Matrix Protein 1 (M1) of the Influenza A virus (UniProt ID: P03485). This 9-mer linear peptide is located within the membrane-binding domain of M1 and is known to be presented on several HLA class I molecules, including: HLA-A*11:01   HLA-A*03:01   HLA-A*31:01   HLA-A*68:01 This epitope has been referenced under IEDB Epitope ID: 58567 and has been widely studied in the context of T cell recognition, MHC class I binding, and antiviral immune responses. Applications: Detection of Influenza-specific CD8⁺ T cells   HLA-A-restricted antigen presentation analysis   Use in T cell activation assays (e.g., ELISPOT, ICS)   Validation of TCR transgenic systems or HLA tetramer tools   Monitoring immune responses in vaccine or infection models Epitope Background This epitope, SIIPSGPLK, is derived from Matrix Protein 1 (M1) of Influenza A virus, a structural protein involved in virion stability, uncoating, and regulation of transcription. The 13–21 region lies within the membrane-binding domain, which interacts with the inner side of the viral lipid bilayer.