Peptides EP07854_1 | Influenza A M1 58-66 (HLA-A*02:01)

品名：Influenza A M1 58-66 (HLA-A*02:01)

货号：EP07854_1

规格：1 mg; 5 mg

品牌：Peptides.de

产品描述

The Influenza A M1 58-66 peptide is a linear peptidic epitope (epitope ID 20354) that has the amino acid sequence GILGFVFTL and is located at positions 58-66 of the Matrix Protein 1 (UniProt:P03485) from Influenza A virus.  The M1 58-66 peptide is highly conserved across many strains of influenza, T cells primed to recognize this peptide can potentially recognize and respond to a variety of influenza infections. This makes the M1 58-66 peptide valuable in vaccine research and in the study of cross-protection against different strains of influenza. The Influenza A M1 58-66 peptide is well-known for its role in being presented by HLA-A*02:01 (a class I MHC molecule) to cytotoxic CD8+ T cells. It is a well-characterized epitope, making it an ideal tool for studying how T cells recognize viral peptides and initiate an immune response. It is used as a model antigen to study T cell function, activation, and the mechanics of antigen presentation. Understanding how immune cells recognize and target antigens also helps improve T cell-based therapies for cancer.  The Influenza A M1 58-66 peptide has been tested in T cell assays, B cell assays and MHC ligand assays. It is frequently used as a positive control, especially in ELISPOT and tetramer staining, ensuring that the immune cells are functioning as expected. The M1 58-66 peptide is also a prime example of an immunodominant epitope. In people with the HLA-A*02:01 type, a significant portion of the immune response to influenza focuses on this peptide, making it a key target for understanding immune system priorities in viral infections.See also an example comparison of our prices with the prices of other peptide manufacturers.