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产品名称 Peptides EP11322_1 | Influenza A M1 59-68 (HLA-A*02:01)
目录号 EP11322_1
别名 Influenza A M1 59-68 (HLA-A*02:01)
外观 见COA
分子量 N/A
CAS N/A
溶解度
存储条件 见COA
保存时间 见COA
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目录号 规格 价格 库存状态  
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Peptides EP11322_1 | Influenza A M1 59-68 (HLA-A*02:01)


品名:Influenza A M1 59-68 (HLA-A*02:01)

货号:EP11322_1

规格:1 mg; 5 mg

品牌:Peptides.de


产品描述

The ILGFVFTLTV peptide (epitope ID 27066) overlaps with the well-known immunodominant epitope GILGFVFTL from Influenza A Matrix Protein 1 (M1; UniProt:P03485). Influenza A MP 59-68 is used for the development of more broadly protective influenza vaccines and as a control peptide in immunological studies.Researchers investigated the immunogenicity and protective efficacy of Modified Vaccinia Virus Ankara (MVA) vectors encoding internal influenza antigens in HLA-A2.1 transgenic mice. Following vaccination with recombinant MVAs expressing peptides derived from Influenza A Matrix Protein 1 (M1), the induced CD8⁺ T cell responses were primarily directed against the immunodominant epitope M1 58-66. However, consistent T cell responses were also observed against the overlapping peptide M1 59-68. CD8⁺ T cell activity was assessed using an IFN-γ ELISPOT assay.


Protein Matrix protein
Species Influenza virus
Application T-cell assays, Immune monitoring, Antigen specific T-cell stimulation, T-cell expansion, Cellular immune response
Indication Infectious disease


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