| 产品名称 | Quartett C-C003/P-C003 | CD117 (QR012) |
|---|---|
| 目录号 | C-C003/P-C003 |
| 别名 | CD117 |
| 外观 | 见COA |
| 分子量 | |
| CAS | |
| 溶解度 | |
| 存储条件 | 见COA |
| 保存时间 | 见COA |
| 备注1 | |
| 备注2 |
Quartett C-C031/P-C031 | CD31 (QR034)
品名：CD117 (QR012) | Recombinant monoclonal rabbit antibody
货号：C-C003/P-C003
品牌：Quartett
规格：0.1 ml; 0.5 ml; 1 ml; 3 ml; 7 ml; 15 ml
产品描述
| Application | IHC (FFPE) | Host | Rabbit |
| Subclass | IgG | Dilution range | 1:100 – 1:200 |
| Cellular localization | Cytoplasm, membrane | Control | Appendix, GIST, skin, tonsil |
| Immunogen | Synthetic peptide from human CD117 | ||
CD117, also known as c-Kit, encodes a receptor tyrosine kinase that is activated by its ligand, stem cell factor, and plays an important role in vital functions such as homeostasis and melanogenesis. CD117 is a proto-oncogene. Mutations and overexpression are associated with several cancers, including gastrointestinal stromal tumors (GIST), mast cell disease, acute myeloid leukemia (AML), small cell lung cancer (SCLC), and Ewing sarcoma. Expression is found in a variety of normal and abnormal cells, such as hematopoietic stem cells, melanocytes, mast cells, germ cells, and skin basal cells.
