| 产品名称 | Quartett C-C025/P-C025 | CD171/L1CAM (QR039) |
|---|---|
| 目录号 | C-C025/P-C025 |
| 别名 | CD171/L1CAM |
| 外观 | 见COA |
| 分子量 | |
| CAS | |
| 溶解度 | |
| 存储条件 | 见COA |
| 保存时间 | 见COA |
| 备注1 | |
| 备注2 |
Quartett C-C031/P-C031 | CD31 (QR034)
品名:CD171/L1CAM (QR039) | Recombinant monoclonal rabbit antibody
货号:C-C025/P-C025
品牌:Quartett
规格:0.1 ml; 0.5 ml; 1 ml; 3 ml; 7 ml; 15 ml
产品描述
| Application | IHC (FFPE) | Host | Rabbit |
| Subclass | IgG | Dilution range | 1:100 – 1:200 |
| Cellular localization | Cytoplasm, membrane | Control | Kidney, gastric carcinoma |
| Immunogen | Synthetic peptide from human CD171/L1CAM | ||
CD171, also known as L1CAM, is a transmembrane protein that functions as a cell adhesion molecule and plays an important role in nervous system development, including neuronal migration and differentiation. CD171 is involved in neuron-neuron adhesion, neurite fasciculation, and neurite outgrowth, among other processes. In addition to the brain, L1CAM is also normally expressed in the renal tubular epithelium, intestinal crypt, and peripheral nerves. L1CAM has been studied in various tumors, including colorectal, renal cell, ovarian, and thyroid carcinomas. Cytoplasmic and membrane expression of L1CAM significantly correlated with poor clinical outcome, defined as aggressive tumor growth, invasion, and an unfavorable prognosis.