| 产品名称 | Quartett C-G003/P-G003 | Glutamine synthetase (QR090) |
|---|---|
| 目录号 | C-G003/P-G003 |
| 别名 | Glutamine synthetase |
| 外观 | 见COA |
| 分子量 | |
| CAS | |
| 溶解度 | |
| 存储条件 | 见COA |
| 保存时间 | 见COA |
| 备注1 | |
| 备注2 |
Quartett C-C031/P-C031 | CD31 (QR034)
品名：Glutamine synthetase (QR090) | Recombinant monoclonal rabbit antibody
货号：C-G003/P-G003
品牌：Quartett
规格：0.1 ml; 0.5 ml; 1 ml; 3 ml; 7 ml; 15 ml
产品描述
| Application | IHC (FFPE) | Host | Rabbit |
| Subclass | IgG | Dilution range | 1:50 – 1:200 |
| Cellular localization | Cytoplasm | Control | Hepatocellular carcinoma, liver |
| Immunogen | Synthetic peptide from human glutamine synthetase | ||
Glutamine synthetase (GS) converts ammonia and glutamate into glutamine. Glutamine synthetase has several metabolic functions. Two of these are the detoxification of ammonia and the regulation of glutamate in neurons. The synthesis and catalytic activity of glutamine synthetase are highly regulated. In the normal liver, GS expression is found in centrilobular (zone 3) hepatocytes, but not in hepatocytes of the middle zone (zone 2) or the periportal zone (zone 3). Glutamine synthetase immunohistochemistry is also positive in neoplasms of hepatocytic origin, such as hepatocellular carcinoma (HCC) and hepatocellular adenoma, making it useful for identifying these tumors.
