| 产品名称 | Quartett C-P010/P-P010 | p16 (QR019) |
|---|---|
| 目录号 | C-P010/P-P010 |
| 别名 | p16 |
| 外观 | 见COA |
| 分子量 | |
| CAS | |
| 溶解度 | |
| 存储条件 | 见COA |
| 保存时间 | 见COA |
| 备注1 | |
| 备注2 |
Quartett C-C031/P-C031 | CD31 (QR034)
品名：p16 (QR019) | Recombinant monoclonal rabbit antibody
货号：C-P010/P-P010
品牌：Quartett
规格：0.1 ml; 0.5 ml; 1 ml; 3 ml; 7 ml; 15 ml
产品描述
| Application | IHC (FFPE) | Host | Rabbit |
| Subclass | IgG | Dilution range | 1:100 – 1:200 |
| Cellular localization | Cytoplasm, nucleus | Control | HPV-infected squamous epithelial cells of the cervix Carcinoma |
| Immunogen | Synthetic peptide from human p16 | ||
p16 is a protein that slows cell division by slowing cell cycle progression from the G1 phase to the S phase, thus acting as a tumor suppressor. A deletion in this gene can result in insufficient or nonfunctional p16, accelerating the cell cycle and leading to the development of many types of cancer. p16 can be used as a biomarker to improve the histological diagnostic accuracy of grade 3 cervical intraepithelial neoplasia (CIN). Expression of p16 (p16-positive) is highly correlated with human papillomavirus (HPV) infection in head and neck squamous cell carcinoma (HNSCC). p16 is also involved in the prevention of melanoma, oropharyngeal squamous cell carcinoma, cervical cancer, vulvar cancer, and esophageal cancer.
