| 产品名称 | Quartett C-S006/P-S006 | STAT6 (QR041) |
|---|---|
| 目录号 | C-S006/P-S006 |
| 别名 | STAT6 |
| 外观 | 见COA |
| 分子量 | |
| CAS | |
| 溶解度 | |
| 存储条件 | 见COA |
| 保存时间 | 见COA |
| 备注1 | |
| 备注2 |
Quartett C-C031/P-C031 | CD31 (QR034)
品名：STAT6 (QR041) | Recombinant monoclonal rabbit antibody
货号：C-S006/P-S006
品牌：Quartett
规格：0.1 ml; 0.5 ml; 1 ml; 3 ml; 7 ml; 15 ml
产品描述
| Application | IHC (FFPE) | Host | Rabbit |
| Subclass | IgG | Dilution range | 1:100 – 1:200 |
| Cellular localization | nucleus | Control | Solitary fibrous tumor |
| Immunogen | Synthetic peptide from human STAT6 | ||
The STAT family consists of seven genes, STAT1 to STAT4, STAT5A, STAT5B, and STAT6, which are involved in the regulation of cell proliferation, apoptosis, angiogenesis, and the immune system response. STAT6 is a transcription factor that performs a dual function: signal transduction and transcriptional activation. It is involved in interleukin-4 signaling and appears to play an important role in cancer. STAT6 has been found to form recurrent fusions with NAB2 on chromosome 12q13 in most solitary fibrous tumors (SFTs), with the exception of meningiomas, hemangioblastomas, schwannomas, and hemangiomas. The fusion allows cytosolic STAT6 to translocate into the nucleus. Detection of nuclear translocation of STAT6 is a hallmark of SFTs and can serve as a diagnostic marker for an NAB2-STAT6 fusion.
