| 产品名称 | Quartett C-V001/P-V001 | Vimentin (QR097) |
|---|---|
| 目录号 | C-V001/P-V001 |
| 别名 | Vimentin |
| 外观 | 见COA |
| 分子量 | |
| CAS | |
| 溶解度 | |
| 存储条件 | 见COA |
| 保存时间 | 见COA |
| 备注1 | |
| 备注2 |
Quartett C-C031/P-C031 | CD31 (QR034)
品名：Vimentin (QR097) | Recombinant monoclonal rabbit antibody
货号：C-V001/P-V001
品牌：Quartett
规格：0.1 ml; 0.5 ml; 1 ml; 3 ml; 7 ml; 15 ml
产品描述
| Application | IHC (FFPE) | Host | Rabbit |
| Subclass | IgG | Dilution range | 1:100 – 1:200 |
| Cellular localization | Cytoplasm | Control | Liver, colon, pancreas |
| Immunogen | Synthetic peptide from human vimentin | ||
Vimentin is a type III intermediate filament protein and part of the cytoskeletal structure. The protein is expressed in mesenchymal cells and in a variety of tumors and cultured cells. It is also expressed in many cells during development. Vimentin plays an important role in cytoskeletal stability and cell integrity. During mitosis, vimentin is phosphorylated by various kinases such as Auroa B, Rho kinases, or Cdk1. The antibody is a marker for mesenchymal cells. It can be used in combination with a panel of antibodies to detect tumors of mesenchymal origin and malignant melanomas. Tumors such as lymphomas and seminomas share the same intermediate filament profile, but vimentin expression is usually weaker.
