| 产品名称 | Quartett C-A001/P-A001 | ALK (QR017) |
|---|---|
| 目录号 | C-A001/P-A001 |
| 别名 | ALK |
| 外观 | 见COA |
| 分子量 | |
| CAS | |
| 溶解度 | |
| 存储条件 | 见COA |
| 保存时间 | 见COA |
| 备注1 | |
| 备注2 |
Quartett C-C031/P-C031 | CD31 (QR034)
品名：ALK (QR017) | Recombinant monoclonal rabbit antibody
货号：C-A001/P-A001
品牌：Quartett
规格：0.1 ml; 0.5 ml; 1 ml; 3 ml; 7 ml; 15 ml
产品描述
| Application | IHC (FFPE) | Host | Rabbit |
| Subclass | IgG | Dilution range | 1:100 – 1:200 |
| Cellular localization | Cytoplasm, nucleus | Control | Anaplastic large cell lymphoma, lung adenocarcinoma with ALK translocation |
| Immunogen | Synthetic peptide from human ALK | ||
ALK (anaplastic lymphoma kinase) belongs to the insulin receptor superfamily. It is a transmembrane receptor protein-tyrosine kinase and can form a fusion protein with the nuclear protein gene nucleiphosmin (NPM). ALK can become active in cancer through several mechanisms. Expression of the protein in tumor cells is an independent prognostic factor predicting a favorable outcome. ALK staining is positive in approximately 60% of anaplastic large cell lymphomas (ALCL). Abnormal expression of the protein has also been observed in various solid tumors, such as non-small cell lung cancer (NSCLC) and brain tumors.
