| 产品名称 | Quartett C-K002/P-K002 | Kappa light chain (QR051) |
|---|---|
| 目录号 | C-K002/P-K002 |
| 别名 | Kappa light chain |
| 外观 | 见COA |
| 分子量 | |
| CAS | |
| 溶解度 | |
| 存储条件 | 见COA |
| 保存时间 | 见COA |
| 备注1 | |
| 备注2 |
Quartett C-C031/P-C031 | CD31 (QR034)
品名：Kappa light chain (QR051) | Recombinant monoclonal rabbit antibody
货号：C-K002/P-K002
品牌：Quartett
规格：0.1 ml; 0.5 ml; 1 ml; 3 ml; 7 ml; 15 ml
产品描述
| Application | IHC (FFPE) | Host | Rabbit |
| Subclass | IgG | Dilution range | 1:100 – 1:200 |
| Cellular localization | Cytoplasm | Control | Tonsil, Lymph node |
| Immunogen | Synthetic peptide from human kappa light chain | ||
B lymphocytes produce immunoglobulins consisting of two identical heavy chains and either two identical kappa light chains or lambda light chains. Normal lymphatic tissue therefore contains a mixture of B cells expressing kappa and lambda light chains in a 2:1 ratio. This ratio is no longer present in B-cell tumors, as they arise from a single transformed cell and therefore express only one type of light chain. The monoclonality of malignant lymphomas is used as a diagnostic marker in detection with the kappa light chain antibody. This antibody labels the kappa light chains of human immunoglobulins expressed by B lymphocytes and plasma cells. It can be helpful in the detection of leukemia, plasmacytomas, and various non-Hodgkin lymphomas. Other cells may also express kappa light chains, which is due to nonspecific uptake of immunoglobulins. The kappa light chain antibody can be used in a panel with lambda light chain.
