| 产品名称 | ReVacc Scientific Y90H86 | Anti-Ebola Glycoprotein Base Monoclonal Neutralizing Antibody (KZ52) |
|---|---|
| 目录号 | Y90H86 |
| 别名 | Anti-Ebola Glycoprotein Base Monoclonal Neutralizing Antibody (KZ52) |
| 外观 | 见COA |
| 分子量 | N/A |
| CAS | N/A |
| 溶解度 | |
| 存储条件 | 见COA |
| 保存时间 | 见COA |
| 备注1 | |
| 备注2 |
| 目录号 | 规格 | 价格 | 库存状态 | |
| Y90H86 | 100 μg; 500 μg | 咨询 | 咨询 |
ReVacc Scientific Y90H86 | Anti-Ebola Glycoprotein Base Monoclonal Neutralizing Antibody (KZ52)
品名：Anti-Ebola Glycoprotein Base Monoclonal Neutralizing Antibody (KZ52)
货号：Y90H86
品牌：ReVacc Scientific
规格：100 μg; 500 μg
产品描述
| Target | Ebola | Epitope | Base of Ebola GP |
| Clonality and isotype | Monoclonal antibody human IgG1 | Conjugate | Unconjugated |
| Description | This antibody was derived from a human survivor of the 1995 Kikwit outbreak of Ebola, and binds to the Ebola virus surface glycoprotein in its trimeric, pre-fusion conformation (GP1+GP2). KZ52 recognizes a protein epitope at the chalice base where it clamps several regions of the pre-fusion GP2 to the amino terminus of GP1. This antibody neutralizes Zaire ebolavirus in vitro by preventing rearrangement of the GP2 HR1A/HR1B segments and blocking host membrane insertion of the internal fusion loop. Alternatively, IgG KZ52 may sterically hinder access to the RBS or to a separate binding site of another cellular factor, especially if multiple attachment events are required for entry (Lee et al. 2009). | ||
| Applications | IF, WB, ELISA, IHC, IP et al. | ||
| Specificity | Ebola | ||
| Form | Liquid in PBS, pH7.2, without preservatives | ||
| Purification | Cell culture supernatant followed by filtration and Protein A purification | ||
| Storage | Shipped at ambient temperature. Stored at 4 °C. | ||
