| 产品名称 | ReVacc Scientific P82C81 | Human Recombinant PD-L1 Protein (Q47E) |
|---|---|
| 目录号 | P82C81 |
| 别名 | Human Recombinant PD-L1 Protein (Q47E) |
| 外观 | 见COA |
| 分子量 | N/A |
| CAS | N/A |
| 溶解度 | |
| 存储条件 | 见COA |
| 保存时间 | 见COA |
| 备注1 | |
| 备注2 |
| 目录号 | 规格 | 价格 | 库存状态 | |
| P82C81 | 100 μg; 500 μg | 咨询 | 咨询 |
ReVacc Scientific P82C81 | Human Recombinant PD-L1 Protein (Q47E)
品名：Human Recombinant PD-L1 Protein (Q47E)
货号：P82C81
品牌：ReVacc Scientific
规格：100 μg；500 μg
产品描述
| Source | Human embryonic kidney HEK cells | Tag | His |
| Organism | - | Biosafety Level | - |
| Applications | Crystallization (Crys), ELISA, SDS-PAGE (SDS), Western Blotting (WB), Immunization or Antibody Sorting Probe, and other biological assays | ||
| Storage | Recommend -80°C storage. Store at 4°C for short-term only. Multiple freeze/Thaw cycles will reduce its activity. | ||
Human PD-L1 (programmed death ligand 1) is commonly expressed on dendritic cells and macrophages, and its ectodomain is composed of a membrane distal IgSF V-set and a membrane proximal IgSF C-set domain. PD-L1 is often overexpressed in different tumors, and its interaction with PD-1 on T cells enables cancer cells to evade T-cell-mediated immune responses. A recombinant form (Phe 19 - Arg 238) of PD-L1 protein (Accession: NP_054862.1) with a mutation of Q47E was produced by human embryonic kidney HEK cells, followed by purification. This product contains a 6 hexa-histidine tag at the C-terminus. The purity has been examined >90% as determined by reducing SDS-PAGE, where protein migrates as 30-35 kDa. We evaluated its binding to anti-His tag antibody (clone RV7, Cat.No. J96C86), and a PD-L1-specific antibody (clone RV59, Cat.No. F16S89) in ELISAs, see results.
