| 产品名称 | ReVacc Scientific J82W46 | Human VEGFR2 Protein (His tag) |
|---|---|
| 目录号 | J82W46 |
| 别名 | Human VEGFR2 Protein (His tag) |
| 外观 | 见COA |
| 分子量 | N/A |
| CAS | N/A |
| 溶解度 | |
| 存储条件 | 见COA |
| 保存时间 | 见COA |
| 备注1 | |
| 备注2 |
| 目录号 | 规格 | 价格 | 库存状态 | |
| J82W46 | 100 μg; 500 μg | 咨询 | 咨询 |
ReVacc Scientific J82W46 | Human VEGFR2 Protein (His tag)
品名:Human VEGFR2 Protein (His tag)
货号:J82W46
品牌:ReVacc Scientific
规格:100 μg;500 μg
产品描述
| Source | Human embryonic kidney HEK cells | Tag | His |
| Applications | Crystallization (Crys), ELISA, SDS-PAGE (SDS), Western Blotting (WB), Immunization or Antibody Sorting Probe, and other biological assays | ||
| Storage | Recommend -80°C storage. Store at 4°C for short-term only. Multiple freeze/Thaw cycles will reduce its activity. | ||
Vascular endothelial growth factor (VEGF) is one of the key players in angiogenesis, the process of new blood vessel formation. VEGF plays role through its two receptors, VEGFR1 and VEGFR2, expressed in endothelial cells. Blocking the interaction between VEGF and its receptors using specific antibodies or other protein entities to prevent signaling has been one of many approaches to reduce tumor growth. A recombinant form (Ala 20 – Glu 764) of VEGFR2 protein (Accession: P35968) was produced by human embryonic kidney HEK cells, followed by purification. This product contains a 6 hexa-histidine tag at the C-terminus. The purity has been examined >90% as determined by reducing SDS-PAGE, where protein migrates as 98 kDa. We evaluated its binding to anti-His tag antibody (clone RV7, Cat.No. J96C86), and a VEGFR2-specific antibody (clone RV62, Cat.No. P11C36) in ELISAs, see results.