ReVacc Scientific S99W4 | VSV-Pseudovirus_ Ebola Zaire strain GP with Luciferase Reporter

品名：VSV-Pseudovirus_ Ebola Zaire strain GP with Luciferase Reporter

货号：S99W4

品牌：ReVacc Scientific

规格：200 μl; 1000 μl

产品描述

Organism：Ebola virus -Related filovirus

This pseudotyped virus uses recombinant vesicular stomatitis virus (rVSV) to carry GP protein of Zaire Ebolavirus Makona strain (GenBank: KR781609.1). As pseudovirus infectivity of rVSV without its original G is restricted to a single round of replication, the pseudotypes can be handled using BSL-2 containment practices. Infection of cells with this pseudotyped virus carrying luciferase reporter results in high level luciferase activity. See our titration result showing that the starting 2-fold diluted pseudovirus generates signal ~ 100,000-fold higher than uninfected control (cell alone as background in blue). A published monoclonal antibody, KZ52, was used to validate its neutralizing activity against this pseudovirus. See picture.