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产品名称 ReVacc Scientific P53F53 | Pseudovirus_RSV Fusion with Luciferase Reporter (VR26 strain)
目录号 P53F53
别名 Pseudovirus_RSV Fusion with Luciferase Reporter (VR26 strain)
外观 见COA
分子量 N/A
CAS N/A
溶解度
存储条件 见COA
保存时间 见COA
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目录号 规格 价格 库存状态  
P53F53 200 μl; 1000 μl 咨询 咨询


ReVacc Scientific P53F53 | Pseudovirus_RSV Fusion with Luciferase Reporter (VR26 strain)


品名:Pseudovirus_RSV Fusion with Luciferase Reporter (VR26 strain)

货号:P53F53

品牌:ReVacc Scientific

规格:200 μl; 1000 μl


产品描述

Organism:Human respiratory syncytial virus (RSV) isolate VR26 strain

This pseudotyped virus uses recombinant vesicular stomatitis virus (rVSV) to carry the full-length fusion (F) protein of Human respiratory syncytial virus (RSV) isolate VR26 strain (UniProtKB/Swiss-Prot: P12568.2). RSV is a respiratory virus with fusion (F) protein as the major target of neutralizing antibodies/vaccine-elicited sera. As pseudovirus infectivity of rVSV without its original G is restricted to a single round of replication, the pseudotypes can be handled using BSL-2 containment practices. Infection of cells with this pseudotyped virus carrying luciferase reporter results in high level luciferase activity. See our titration result showing that the starting 2-fold diluted pseudovirus generates signal ~ 10,000-fold higher than uninfected control (cell alone as background in blue). Three known neutralizing mAb (101F) was used to validate its neutralizing activity against this pseudovirus. See picture.

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