Synthelis | PL024 | C-C chemokine receptor type 5

品名：C-C chemokine receptor type 5(CCR5)

货号：PL024

规格：10µg, 20µg ,100 µg , 200 µg, 500 µg,bulk

品牌：Synthelis

产品描述

CCR5 is a receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates. CCR5 is G protein-coupled receptor (GPCR) which regulates trafficking and effector functions of memory/effector T lymphocytes, macrophages, and immature dendritic cells. It also serves as the main coreceptor for the entry of R5 strains of human immunodeficiency virus (HIV-1, HIV-2).