Synthelis | D029 | Voltage-Dependent Anion Channel 1

品名：Voltage-Dependent Anion Channel 1(VDAC1 – Detergent)

货号：D029

规格：10 µg, 50 µg, 100 µg

品牌：Synthelis

产品描述

VDAC-1 (Voltaged-Dependent Anion Channel) is a mitochondrial porin located in the outer mitochondrial membrane (OMM). This protein consists of a transmembrane β-barrel with an N-terminal α-helix. VDAC is responsible for the exchange of adenine nucleotides, Ca²+ and other metabolites across the mitochondrial membrane. It also has binding sites for glycerol, hexokinase II, creatine kinase and Bcl-2 family members. VDAC plays a central role in the increase of mitochondrial membrane permeability as part of apoptosis.