品名：Seraseq® Whole Transcriptome RNA Seq Mix

货号：0710-2129

品牌：SeraCare 

Product Specifications

# of Fusions：22 

Concentration：50 ng/µl 

Fill Volume：20 µl 

Total Mass：1 ug 

Format：Purified RNA 

Buffer：1mM Tris; pH 8

Details

INTRODUCTION 

Whole transcriptome RNA sequencing allows for the analysis of fusion genes with potential clinical utility that 

currently cannot be detected using the limited genomic coverage of targeted NGS panels. Additionally, some 

clinical cancer testing labs are evaluating whole transcriptome panels for improved diagnostic yields and clinical 

utilization for NGS-based tumor profiling test reimbursements. Expanding fusion gene content and higher 

detection efficiencies will expand use of fusion analysis in clinical NGS applications. Maybe most importantly is 

that new therapies are targeting fusion genes as clinical biomarkers for treatments of various adult and 

pediatric cancers. 

LGC SeraCare has developed a novel whole transcriptome RNA sequencing reference material for analysis of 22 

fusion genes with clinical applications in oncology as analyzed by a whole transcriptome NGS assay. Such assays 

provide a comprehensive view of the transcriptome with ability to detect known and novel fusions of clinical 

utility. This reference material is offered as a purified RNA mix with high titer concentration for all 22 RNA 

fusion constructs. 

FEATURES AND BENEFITS  

   Single sample with 22 clinically-relevant RNA gene fusions. 

   Purified RNA format ready for total RNA transcriptome sequencing library prep. 

   Fusion copies accurately quantitated using digital PCR. 

   Fusion constructs blended into total RNA from well-characterized GM24385 cell line as wild-type background. 

   Manufactured in GMP-compliant and ISO 13485-certified facilities. 

   Product Specifications - Whole Transcriptome RNA Seq Mix 

维百奥生物代理SeraCare对照及参比物质。

维百奥（北京）生物科技有限公司，自2018年与SeraCare（现隶属于LGC Clinical Diagnostics）合作以来，长期为中国客户

提供包括SeraSeq系列参比物质，领域包括肿瘤、生殖健康和遗传病。SeraCare研发和生产一系列临床参比物质，可以用于任何

研发阶段，以确保临床基因组学检测结果的准确性。

SeraCare参比物质涵盖的范围：

1）Next Generation Sequencing

2）Sanger Sequencing

3）Real-time PCR and digital PCR (dPCR)

4）Microarray

主要特点

1）Ready-to-use reference materials covering clinically-relevant variants and all variant types - SNVs, INDELS, CNVs, 

and RNA fusions

2）Highly multiplexed - provide significantly more data per NGS run, saving sequencing costs

3）Available in multiple formats to suite different workflow needs - purified DNA & RNA, ctDNA, encapsulated ctDNA 

in plasma, and FFPE

4）Manufactured in cGMP-compliant, ISO 13485-certified facilities

5）Stringent product release testing - all variants qualified by dPCR for allele frequencies or copy numbers