维百奥(北京)生物科技有限公司

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产品名称 Seraseq® Tumor Mutation DNA Mix v2 AF 10 HC (SeraCare)
目录号 0710-0094
别名 N/A
外观 N/A
分子量 N/A
CAS N/A
溶解度 N/A
存储条件 N/A
保存时间 N/A
备注1 N/A
备注2 N/A
目录号 规格 价格 库存状态  
0710-0094 1 x 25 µl 咨询客服 咨询客服

品名:Seraseq® Tumor Mutation DNA Mix v2 AF 10 HC

货号:0710-0094 

品牌:SeraCare


Product Specifications

                               Gene List

AKTI          FGFR3        JAK2                PDGFRA  

APC           FLT3           KIT                   PIK3CA 

ATM          FOXL2        KRAS                PTEN 

BRAF         GNA11       MPL                 RET 

CTNNB1    GNAQ       NCOA4-RET      SMAD4 

EGFR         GNAS        NPM1                TP53 

ERBB2        IDH1         NRAS/CSDE1    TPR-ALK


Details 

The Seraseq Tumor Mutation DNA Mix v2 (AF10) HC is a multiplexed mixture of actionable biosynthetic DNA 

targets precisely blended with a single, well-characterized genomic background. This product is produced 

under rigorous design control and manufacturing practices to an allelic frequency of 10%, and is offered in 

a high concentration (HC) format at 25 ng/µL. Designed to assess the overall performance of your somatic 

mutation assay by next-generation sequencing (NGS), this unique product includes a wide range of single 

nucleotide variants (SNVs), insertion-deletion mutations (indels), and structural variants (SVs). 


        Single-vial format for daily run use

        40 unique multiplexed variants across 28 genes (see table in Specifications tab) 

                     20 SNVs 

                     5 SNVs that are part of homopolymers 

                     13 indels 

                     2 SVs 

        Mutation targets quantitated with digital PCR 

        Well-characterized GM24385 human genomic DNA as background wild-type material 

        Manufactured within cGMP-compliant, ISO 13485-certified facilities 



The Seraseq Tumor Mutation Mix-II DNA Mix v2 (AF10) HC is formulated for use with targeted next-generation 

sequencing (NGS) assays that detect mutations in key oncogenes and tumor suppressor genes. 

The Seraseq Tumor Mutation Mix-II DNA Mix v2 (AF10) HC is intended as a quality reference material for 

translational and disease research testing to monitor library preparation, sequencing, and variant allele detection 

under a given set of bioinformatics pipeline parameters. 


For research use only. Not for use in diagnostic procedures.



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维百奥生物代理SeraCare对照及参比物质。


维百奥(北京)生物科技有限公司,自2018年与SeraCare(现隶属于LGC Clinical Diagnostics)合作以来,长期为中国客户

提供包括SeraSeq系列参比物质,领域包括肿瘤、生殖健康遗传病。SeraCare研发和生产一系列临床参比物质,可以用于任何

研发阶段,以确保临床基因组学检测结果的准确性。

 

SeraCare参比物质涵盖的范围:

1)Next Generation Sequencing

2)Sanger Sequencing

3)Real-time PCR and digital PCR (dPCR)

4)Microarray

 

主要特点

1)Ready-to-use reference materials covering clinically-relevant variants and all variant types - SNVs, INDELS, CNVs, 

and RNA fusions

2)Highly multiplexed - provide significantly more data per NGS run, saving sequencing costs

3)Available in multiple formats to suite different workflow needs - purified DNA & RNA, ctDNA, encapsulated ctDNA 

in plasma, and FFPE

4)Manufactured in cGMP-compliant, ISO 13485-certified facilities

5)Stringent product release testing - all variants qualified by dPCR for allele frequencies or copy numbers

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