产品名称 | Seraseq® Tumor Mutation DNA Mix v2 AF 10 HC (SeraCare) |
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目录号 | 0710-0094 |
别名 | N/A |
外观 | N/A |
分子量 | N/A |
CAS | N/A |
溶解度 | N/A |
存储条件 | N/A |
保存时间 | N/A |
备注1 | N/A |
备注2 | N/A |
目录号 | 规格 | 价格 | 库存状态 | |
0710-0094 | 1 x 25 µl | 咨询客服 | 咨询客服 |
品名:Seraseq® Tumor Mutation DNA Mix v2 AF 10 HC
货号:0710-0094
品牌:SeraCare
Product Specifications
Gene List
AKTI FGFR3 JAK2 PDGFRA
APC FLT3 KIT PIK3CA
ATM FOXL2 KRAS PTEN
BRAF GNA11 MPL RET
CTNNB1 GNAQ NCOA4-RET SMAD4
EGFR GNAS NPM1 TP53
ERBB2 IDH1 NRAS/CSDE1 TPR-ALK
Details
The Seraseq Tumor Mutation DNA Mix v2 (AF10) HC is a multiplexed mixture of actionable biosynthetic DNA
targets precisely blended with a single, well-characterized genomic background. This product is produced
under rigorous design control and manufacturing practices to an allelic frequency of 10%, and is offered in
a high concentration (HC) format at 25 ng/µL. Designed to assess the overall performance of your somatic
mutation assay by next-generation sequencing (NGS), this unique product includes a wide range of single
nucleotide variants (SNVs), insertion-deletion mutations (indels), and structural variants (SVs).
Single-vial format for daily run use
40 unique multiplexed variants across 28 genes (see table in Specifications tab)
20 SNVs
5 SNVs that are part of homopolymers
13 indels
2 SVs
Mutation targets quantitated with digital PCR
Well-characterized GM24385 human genomic DNA as background wild-type material
Manufactured within cGMP-compliant, ISO 13485-certified facilities
The Seraseq Tumor Mutation Mix-II DNA Mix v2 (AF10) HC is formulated for use with targeted next-generation
sequencing (NGS) assays that detect mutations in key oncogenes and tumor suppressor genes.
The Seraseq Tumor Mutation Mix-II DNA Mix v2 (AF10) HC is intended as a quality reference material for
translational and disease research testing to monitor library preparation, sequencing, and variant allele detection
under a given set of bioinformatics pipeline parameters.
For research use only. Not for use in diagnostic procedures.
维百奥生物代理SeraCare对照及参比物质。
维百奥(北京)生物科技有限公司,自2018年与SeraCare(现隶属于LGC Clinical Diagnostics)合作以来,长期为中国客户
提供包括SeraSeq系列参比物质,领域包括肿瘤、生殖健康和遗传病。SeraCare研发和生产一系列临床参比物质,可以用于任何
研发阶段,以确保临床基因组学检测结果的准确性。
SeraCare参比物质涵盖的范围:
1)Next Generation Sequencing
2)Sanger Sequencing
3)Real-time PCR and digital PCR (dPCR)
4)Microarray
主要特点
1)Ready-to-use reference materials covering clinically-relevant variants and all variant types - SNVs, INDELS, CNVs,
and RNA fusions
2)Highly multiplexed - provide significantly more data per NGS run, saving sequencing costs
3)Available in multiple formats to suite different workflow needs - purified DNA & RNA, ctDNA, encapsulated ctDNA
in plasma, and FFPE
4)Manufactured in cGMP-compliant, ISO 13485-certified facilities
5)Stringent product release testing - all variants qualified by dPCR for allele frequencies or copy numbers