维百奥(北京)生物科技有限公司

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产品名称 Seraseq® TNA (DNA/RNA) WT Mix (SeraCare)
目录号 0710-1580
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目录号 规格 价格 库存状态  
0710-1580 2 x 20 µl 咨询客服 咨询客服

品名:Seraseq® TNA (DNA/RNA) WT Mix

货号:0710-1580

品牌:SeraCare 


Product Specifications

Concentration:2 x 25 ng/ul 

Fill Volume:2 x 20 µ1 

DNA Size:500 ng 

RNA Size:500 ng


Details

Molecular assays that profile tumor mutations in solid tissue biopsies require an efficient and precise evaluation 

of the pre-analytic portion of their workflow prior to downstream analysis by NGS or other methods. The use of 

contrived reference material or cell line-based control provides a critical input to the optimization of nucleic acid

extraction from very challenging FFPE tissue materials without wasting precious mutation-positive tissue samples. 

We have developed two formats of total nucleic acid (TNA) derived from GM24385 human cell line as negative 

sample reference materials for use in targeted NGS assays. The cell line is applied as the WT background in all 

existing Seraseq tumor DNA and RNA products. As a negative reference material, we have extracted DNA and RNA 

from GM24385 as a buffered mix (TNA WT) as well as a formalin fixed and paraffin embedded option (FFPE curls) 

to support labs validating assay specificity at wildtype base positions, as well as specificity at positions affected by 

mutations included in all of the Seraseq RNA and DNA (Mutation Mix and Reference Material) products. 


      Cell line-based negative (WT) sample reference material 

      Offered as purified and ready-to-use RNA and DNA (up to 1 µg) in targeted NGS assay workflows 

      Well characterized GM 24385 wild-type human cell line material 

      Manufactured in GMP-compliant ISO 13485 certified facility 



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维百奥生物代理SeraCare对照及参比物质。


维百奥(北京)生物科技有限公司,自2018年与SeraCare(现隶属于LGC Clinical Diagnostics)合作以来,长期为中国客户

提供包括SeraSeq系列参比物质,领域包括肿瘤、生殖健康遗传病。SeraCare研发和生产一系列临床参比物质,可以用于任何

研发阶段,以确保临床基因组学检测结果的准确性。

 

SeraCare参比物质涵盖的范围:

1)Next Generation Sequencing

2)Sanger Sequencing

3)Real-time PCR and digital PCR (dPCR)

4)Microarray

 

主要特点

1)Ready-to-use reference materials covering clinically-relevant variants and all variant types - SNVs, INDELS, CNVs, 

and RNA fusions

2)Highly multiplexed - provide significantly more data per NGS run, saving sequencing costs

3)Available in multiple formats to suite different workflow needs - purified DNA & RNA, ctDNA, encapsulated ctDNA 

in plasma, and FFPE

4)Manufactured in cGMP-compliant, ISO 13485-certified facilities

5)Stringent product release testing - all variants qualified by dPCR for allele frequencies or copy numbers

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