品名：Seraseq® Solid Tumor CNV Mix, +3 copies

货号：0710-2866

品牌：SeraCare 

Product Specifications

# of CNVs ：12(AKT2BRAFEGFRERBB2FGFR3KITKRAS,MET,MYC,MYCN,NTRK1,PIK3CA) 

Copy Number：+3 copies of each gene 

Format：1 mM Tris, 0.1 mM EDTA, 10 mM KCl, pH 8.0 

Size：1x20 pL 

Concentration：10 ng/L

Details

Gene amplifications and deletions, collectively called copy number variations (CNVs), are common in cancer cells 

and contribute to uncontrolled cell growth, drug sensitivity and resistance. To support clinical labs performing 

NGS-based tumor profiling of cancer patient samples and help assay developers develop and characterize the 

performance of their assays, LGCSeraCare has developed a comprehensive solid tumor CNV reference material in 

mutation mix format. 

       FEATURES AND BENEFITS 

12 clinically relevant CNVs associated with solid tumors 

A single reference material carrying gene amplifications at various levels 

Copy numbers quantified using sensitive dPCR assays and blended with the well-characterized GM24385 

genomic background 

Validated by a targeted NGS panel Manufactured in GMP-compliant, ISO 13485-certified facilities 

This specific CNV mix includes +3 copies 

维百奥生物代理SeraCare对照及参比物质。

维百奥（北京）生物科技有限公司，自2018年与SeraCare（现隶属于LGC Clinical Diagnostics）合作以来，长期为中国客户

提供包括SeraSeq系列参比物质，领域包括肿瘤、生殖健康和遗传病。SeraCare研发和生产一系列临床参比物质，可以用于任何

研发阶段，以确保临床基因组学检测结果的准确性。

SeraCare参比物质涵盖的范围：

1）Next Generation Sequencing

2）Sanger Sequencing

3）Real-time PCR and digital PCR (dPCR)

4）Microarray

主要特点

1）Ready-to-use reference materials covering clinically-relevant variants and all variant types - SNVs, INDELS, CNVs, 

and RNA fusions

2）Highly multiplexed - provide significantly more data per NGS run, saving sequencing costs

3）Available in multiple formats to suite different workflow needs - purified DNA & RNA, ctDNA, encapsulated ctDNA 

in plasma, and FFPE

4）Manufactured in cGMP-compliant, ISO 13485-certified facilities

5）Stringent product release testing - all variants qualified by dPCR for allele frequencies or copy numbers