品名：Seraseq® NTRK Fusion RNA Mix 

货号：0710-1696

品牌：SeraCare 

Product Specifications

# of variants：15 

Concentration:25 ng/µL 

Fill Size：20 µl 

Total DNA：500 ng 

Number of vials：1 

Matrix：TE Buffer

Details

Neurotrophic tyrosine receptor kinases (NTRK) can become abnormally fused to other genes resulting in growth 

signals that can lead to cancer in many organs of the human body. Anti-tumor drugs that target NTRK fusions 

have been shown to be largely effective across many tumor types regardless of patient age (adult or pediatric), 

especially in locally advanced or metastatic solid tumors. This product expands SeraCare's RNA Fusion FFPE

reference material product portfolio to support routine clinical diagnostic / companion diagnostic (CDx) use for 

solid tumor testing of tissue biopsies for NTRK fusion genes in cancer disease diagnosis and treatment selection. 

    15 clinically-relevant NTRK fusion genes in a single reference sample 

    Offered as purified RNA (spike-in mix) or FFPE for full process NGS assay validation and positive sample control 

    Fusions precisely quantitated with digital PCR 

    Well-characterized GM24385 human genomic RNA as background wild-type material 

    Manufactured in GMP-compliant and ISO 13485-certified facility. 

维百奥生物代理SeraCare对照及参比物质。

维百奥（北京）生物科技有限公司，自2018年与SeraCare（现隶属于LGC Clinical Diagnostics）合作以来，长期为中国客户

提供包括SeraSeq系列参比物质，领域包括肿瘤、生殖健康和遗传病。SeraCare研发和生产一系列临床参比物质，可以用于任何

研发阶段，以确保临床基因组学检测结果的准确性。

SeraCare参比物质涵盖的范围：

1）Next Generation Sequencing

2）Sanger Sequencing

3）Real-time PCR and digital PCR (dPCR)

4）Microarray

主要特点

1）Ready-to-use reference materials covering clinically-relevant variants and all variant types - SNVs, INDELS, CNVs, 

and RNA fusions

2）Highly multiplexed - provide significantly more data per NGS run, saving sequencing costs

3）Available in multiple formats to suite different workflow needs - purified DNA & RNA, ctDNA, encapsulated ctDNA 

in plasma, and FFPE

4）Manufactured in cGMP-compliant, ISO 13485-certified facilities

5）Stringent product release testing - all variants qualified by dPCR for allele frequencies or copy numbers