品名：Seraseq® gDNA MSI-High Mix 

货号：0710-0408 

品牌：SeraCare 

Product Specifications

# of Variants：23 

Allele Frequency：Variants at either 5%, 10%, or 15% 

Concentrations：15 ng/µL 

Amount：375 ng (single vial) 

Buffer：1 mM Tris / 0.1 mM EDTA pH 8.0

Details

Molecular analysis of myeloid cancers, such as acute myeloid leukemia (AML) and chronic myeloid leukemia (CML), 

is rapidly shifting from single-site methods such as FISH and qPCR to highly-multiplexed next-generation 

sequencing (NGS) assays. Hence, there is an increasing demand for highly multiplexed, patient-like NGS reference 

materials covering a broad range of clinically relevant variants in order to ensure that new and existing myeloid assays 

are robust, accurate, and consistent. SeraCare has developed the industry's first comprehensive set of myeloid cancer 

reference materials in response to this critical market need. 

Single sample with 23 clinically-relevant DNA mutations across 16 genes (save $1000s in running costs) 

Expert-designed to ensure coverage across important variants (mix of SNVs, indels, and ITD) at relevant allele 

frequencies 

Built with innovative technology to produce patient-like sample characteristics and NGS assay performance 

Mutation targets precisely quantitated with digital PCR Single well-characterized GM24385 cell line as background 

wild-type material 

Manufactured in GMP-compliant and ISO 13485-certified facilities 

维百奥生物代理SeraCare对照及参比物质。

维百奥（北京）生物科技有限公司，自2018年与SeraCare（现隶属于LGC Clinical Diagnostics）合作以来，长期为中国客户

提供包括SeraSeq系列参比物质，领域包括肿瘤、生殖健康和遗传病。SeraCare研发和生产一系列临床参比物质，可以用于任何

研发阶段，以确保临床基因组学检测结果的准确性。

SeraCare参比物质涵盖的范围：

1）Next Generation Sequencing

2）Sanger Sequencing

3）Real-time PCR and digital PCR (dPCR)

4）Microarray

主要特点

1）Ready-to-use reference materials covering clinically-relevant variants and all variant types - SNVs, INDELS, CNVs, 

and RNA fusions

2）Highly multiplexed - provide significantly more data per NGS run, saving sequencing costs

3）Available in multiple formats to suite different workflow needs - purified DNA & RNA, ctDNA, encapsulated ctDNA 

in plasma, and FFPE

4）Manufactured in cGMP-compliant, ISO 13485-certified facilities

5）Stringent product release testing - all variants qualified by dPCR for allele frequencies or copy numbers