品名：Seraseq® gDNA MSI-High Mix 

货号：0710-2647 

品牌：SeraCare 

Product Specifications

# of Variants：25 

Allele Frequency：0.1% 

Concentrations：15 ng/µL 

Amount：375 ng (single vial) 

Buffer：1 mM Tris, 0.1 mM EDTA, 10 mM KCl, pH 8.0

Details

To help clinical labs performing NGS-based myeloid testing characterize the limit of detection (LOD) of their 

liquid biopsy assays and validate robust sensitivity, SeraCare has developed myeloid cancer NGS reference 

material in ctDNA format to ensure compatibility with existing and emerging myeloid assays. 

Single sample with 25 clinically relevant DNA variants across 17 genes 

Expert-designed to ensure coverage across important variants (mix of SNVs, INDELs, and ITD) at relevant 

allele frequencies (1%, 0.5%, 0.1%, WT) 

Built with innovative technology to produce patient-like sample performance in NGS assays 

Variants precisely quantified using highly sensitive digital PCR assays, and blended with a single 

well-characterized genomic background (GM24385) 

Validated by targeted NGS panels 

Manufactured in GMP-compliant, ISO 13485-certified facilities 

维百奥生物代理SeraCare对照及参比物质。

维百奥（北京）生物科技有限公司，自2018年与SeraCare（现隶属于LGC Clinical Diagnostics）合作以来，长期为中国客户

提供包括SeraSeq系列参比物质，领域包括肿瘤、生殖健康和遗传病。SeraCare研发和生产一系列临床参比物质，可以用于任何

研发阶段，以确保临床基因组学检测结果的准确性。

SeraCare参比物质涵盖的范围：

1）Next Generation Sequencing

2）Sanger Sequencing

3）Real-time PCR and digital PCR (dPCR)

4）Microarray

主要特点

1）Ready-to-use reference materials covering clinically-relevant variants and all variant types - SNVs, INDELS, CNVs, 

and RNA fusions

2）Highly multiplexed - provide significantly more data per NGS run, saving sequencing costs

3）Available in multiple formats to suite different workflow needs - purified DNA & RNA, ctDNA, encapsulated ctDNA 

in plasma, and FFPE

4）Manufactured in cGMP-compliant, ISO 13485-certified facilities

5）Stringent product release testing - all variants qualified by dPCR for allele frequencies or copy numbers