维百奥(北京)生物科技有限公司

400-001-2615
info@vicbio.com
产品名称 Seraseq® HRD gDNA Low-Positive Mix (SeraCare)
目录号 0710-2880
别名 N/A
外观 N/A
分子量 N/A
CAS N/A
溶解度 N/A
存储条件 N/A
保存时间 N/A
备注1 N/A
备注2 N/A
目录号 规格 价格 库存状态  
0710-2880 2 x 20 µl 咨询客服 咨询客服

品名:Seraseq® HRD gDNA Low-Positive Mix

货号:0710-2880

品牌:SeraCare


Product Specifications - gDNA HRD Low-Positive Mix 

GIS#:58 

Number of genes:4(ATM,BRIP,RAD51C,RAD51D) 

Number of variants:8(4 SNVs, 3 insertions,1 deletion) 

Format:gDNA 

Size:2 x500 ng(25 ng/ul; tumor and normal matched) 


#Genomic Instability Score (GIS) calculated using Illumina TruSight™ Oncology (TSO) 500 HRD RUO assay which 

calculates a GIS using an algorithm licensed from Myriad Genetics. Illumina TSO 500 HRD is not available in Japan.


Details 

Genomic instability resulting from homologous recombination DNA repair deficiency (HRD) is a response biomarker

to assess ovarian and breast cancer patient eligibility for PARP inhibitor and platinum-based therapies. HRD 

measurements have the potential to improve cancer therapy, however standardizing and democratizing HRD 

measurements remains challenging due to their inherent complexity. This cell line-derived HRD reference material 

can support the development, validation, and routine use of assays determining HRD status in cancer patients. 


FEATURES 


Derived from tumor and matched-normal human cell lines 

Allows blending to desired % tumor content with included SNP-matched normal cell line gDNA 20 µL of both tumor and 

matched normal gDNA at 25 ng/µL 

HRD status validated by targeted Next Generation Sequencing (NGS) 

Manufactured in GMP-compliant, ISO 13485-certified facilities 


                                                        65ab095e3a4b3.png

维百奥生物代理SeraCare对照及参比物质。


维百奥(北京)生物科技有限公司,自2018年与SeraCare(现隶属于LGC Clinical Diagnostics)合作以来,长期为中国客户

提供包括SeraSeq系列参比物质,领域包括肿瘤、生殖健康遗传病。SeraCare研发和生产一系列临床参比物质,可以用于任何

研发阶段,以确保临床基因组学检测结果的准确性。

 

SeraCare参比物质涵盖的范围:

1)Next Generation Sequencing

2)Sanger Sequencing

3)Real-time PCR and digital PCR (dPCR)

4)Microarray

 

主要特点

1)Ready-to-use reference materials covering clinically-relevant variants and all variant types - SNVs, INDELS, CNVs, 

and RNA fusions

2)Highly multiplexed - provide significantly more data per NGS run, saving sequencing costs

3)Available in multiple formats to suite different workflow needs - purified DNA & RNA, ctDNA, encapsulated ctDNA 

in plasma, and FFPE

4)Manufactured in cGMP-compliant, ISO 13485-certified facilities

5)Stringent product release testing - all variants qualified by dPCR for allele frequencies or copy numbers

相关产品