品名：Seraseq® ctDNA Reference Material v2 AF0.5%

货号：0710-0205

品牌：SeraCare 

Product Specifications 

# of Variants：40 

Allele Frequency：0.5% 

Fragment Size：~170bp  average 

Concentration：25 ng/mL 

Volume：5 mL 

Total DNA：125 ng (single vial) 

Matrix：SeraCon™ Matribase (human plasma-like) 

Archer® is a registered trademark, and Reveal ctDNA™ is a trademark of ArcherDx, Inc. 

Oncomine® is a registered trademark of Thermo Fisher Scientific. 

UltraSEEK™ is a trademark of Agena Bioscience, Inc.

Details

To overcome the lack of patient-like reference materials for liquid biopsy, including drawbacks of existing 

methodologies such as sonication, SeraCare has developed a breakthrough technology that produces the 

most patient-like materials compared to native ctDNA. The Seraseq ctDNA Mutation Mix v2 is a highly 

multiplexed product for NGS-based ctDNA assays targeting cancer-relevant somatic mutations. 

This specific ctDNA Reference Material v2 product has an allele frequency of 0.5%. 

      Size distribution, library yield and complexity consistent with native ctDNA 

      Single sample with 40 clinically-relevant mutations across 28 genes, all at the same specified allele frequency 

      Offered in a full-process plasma-like material capable of assessing the entire workflow from extractio

through analysis 

      Mutation targets precisely quantitated with digital PCR 

      Single well-characterized GM24385 human genomic DNA as background wild-type material 

      Manufactured in GMP-compliant and ISO 13485-certified facilities

维百奥生物代理SeraCare对照及参比物质。

维百奥（北京）生物科技有限公司，自2018年与SeraCare（现隶属于LGC Clinical Diagnostics）合作以来，长期为中国客户

提供包括SeraSeq系列参比物质，领域包括肿瘤、生殖健康和遗传病。SeraCare研发和生产一系列临床参比物质，可以用于任何

研发阶段，以确保临床基因组学检测结果的准确性。

SeraCare参比物质涵盖的范围：

1）Next Generation Sequencing

2）Sanger Sequencing

3）Real-time PCR and digital PCR (dPCR)

4）Microarray

主要特点

1）Ready-to-use reference materials covering clinically-relevant variants and all variant types - SNVs, INDELS, CNVs, 

and RNA fusions

2）Highly multiplexed - provide significantly more data per NGS run, saving sequencing costs

3）Available in multiple formats to suite different workflow needs - purified DNA & RNA, ctDNA, encapsulated ctDNA

in plasma, and FFPE

4）Manufactured in cGMP-compliant, ISO 13485-certified facilities

5）Stringent product release testing - all variants qualified by dPCR for allele frequencies or copy numbers