维百奥(北京)生物科技有限公司

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产品名称 Seraseq® ctDNA Complete™ Mutation Mix AF0.1% (SeraCare)
目录号 0710-0532
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目录号 规格 价格 库存状态  
0710-0532 1 x 25 µl 咨询客服 咨询客服

品名:Seraseq® ctDNA Complete™ Mutation Mix AF0.1%

货号:0710-0532

品牌:SeraCare


Product Specifications 

# of Variants 25 

Allele Frequency 0.1% 

Fragment Size ~170bp 

Concentration 10ng/µL 

Fill Size 25 µL 

Total DNA 250 ng 

Buffer Tris/EDTA (TE) NGS-Based Assay 

1706074610663820.png

Archer® is a registered trademark, and Reveal ctDNA™ is a trademark of ArcherDx, Inc. 

Oncomine® is a registered trademark of Thermo Fisher Scientific. 

UltraSEEK™ is a trademark of Agena Bioscience, Inc.


Details

To further accelerate the validation and clinical application of liquid biopsy-based ccfDNA-targeted NGS assays, 

SeraCare has developed the Seraseq ctDNA Complete that expands coverage of all relevant variant types including 

SNVs, INDELs, CNVs, and gene fusions in a single highly-multiplexed reference sample. These new products are 

offered in either a purified ctDNA format or a plasma-like matrix format, all precisely quantitated by digital PCR 

against a single well-characterized genomic background (GM24385), and orthogonally validated with NGS 

technology. 


This specific ctDNA Complete product has an allele frequency of 0.1%. 

25 unique multiplexed variants in 16 genes, covering 12 SNVs, 7 INDELs, 3 CNVs, and 3 SVs, in purified and 

plasma-like matrix formats. 

6 different allele frequencies available: wild-type, 0.1%, 0.5%, 1%, 2.5%, and 5% 

Allows end-to-end evaluation of assay performance across the entire workflow, including pre-analytic extraction 

steps 

Variants quantitated with digital PCR and orthogonally validated by NGS 

Blends with well-characterized GM24385 human genomic DNA as background wild-type material 

Manufactured within cGMP-compliant and ISO 13485-certified facilities.


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维百奥生物代理SeraCare对照及参比物质。


维百奥(北京)生物科技有限公司,自2018年与SeraCare(现隶属于LGC Clinical Diagnostics)合作以来,长期为中国客户

提供包括SeraSeq系列参比物质,领域包括肿瘤、生殖健康遗传病。SeraCare研发和生产一系列临床参比物质,可以用于任何

研发阶段,以确保临床基因组学检测结果的准确性。

 

SeraCare参比物质涵盖的范围:

1)Next Generation Sequencing

2)Sanger Sequencing

3)Real-time PCR and digital PCR (dPCR)

4)Microarray

 

主要特点

1)Ready-to-use reference materials covering clinically-relevant variants and all variant types - SNVs, INDELS, CNVs, 

and RNA fusions

2)Highly multiplexed - provide significantly more data per NGS run, saving sequencing costs

3)Available in multiple formats to suite different workflow needs - purified DNA & RNA, ctDNA, encapsulated ctDNA 

in plasma, and FFPE

4)Manufactured in cGMP-compliant, ISO 13485-certified facilities

5)Stringent product release testing - all variants qualified by dPCR for allele frequencies or copy numbers

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