品名：Seraseq® Trisomy 21 Female-Matched Reference Material

货号：0720-0168

品牌：SeraCare 

Details

Non-invasive prenatal testing (NIPT) continues to expand globally, and given the clinical implications, it is 

extremely critical that NIPT assays report back presence or absence of aneuploidies in an accurate and 

consistent manner. Matched maternal-fetal reference materials derived from pregnant maternal plasma 

enable accurate assessment of a broad range of NIPT assays, including those based on counting methods, 

SNPs, as well as differences in the length of maternal and fetal cfDNA. The Seraseq Trisomy 21 

Female - Matched Reference Material can be used to develop a new test, validate an assay, monitor routine 

performance, troubleshoot problems across the entire workflow and ensure overall proficiency with the same 

sustainable product. Matched (or related) maternal-fetal Trisomy 21 (or Down Syndrome) male sample 

compatible with a broad range of NIPT assay methods - Proprietary method maintains native cfDNA size profile 

of ~170 bp size distribution and natural maternal-fetal size difference - Offered in a plasma format capable of 

assessing the entire workflow from extraction through analysis (identical to clinical samples) - Fetal fraction levels 

confirmed to be moderate-high positive to help establish initial baseline (can be customized to lower levels) - 

Manufactured in GMP-compliant and ISO 13485-certified facilities.

维百奥生物代理SeraCare对照及参比物质。

维百奥（北京）生物科技有限公司，自2018年与SeraCare（现隶属于LGC Clinical Diagnostics）合作以来，长期为中国客户

提供包括SeraSeq系列参比物质，领域包括肿瘤、生殖健康和遗传病。SeraCare研发和生产一系列临床参比物质，可以用于任何

研发阶段，以确保临床基因组学检测结果的准确性。

SeraCare参比物质涵盖的范围：

1）Next Generation Sequencing

2）Sanger Sequencing

3）Real-time PCR and digital PCR (dPCR)

4）Microarray

主要特点

1）Ready-to-use reference materials covering clinically-relevant variants and all variant types - SNVs, INDELS, CNVs, 

and RNA fusions

2）Highly multiplexed - provide significantly more data per NGS run, saving sequencing costs

3）Available in multiple formats to suite different workflow needs - purified DNA & RNA, ctDNA, encapsulated ctDNA

in plasma, and FFPE

4）Manufactured in cGMP-compliant, ISO 13485-certified facilities

5）Stringent product release testing - all variants qualified by dPCR for allele frequencies or copy numbers