品名：Seraseq® Trisomy 18 Female-Matched Reference Material 

货号：0720-0172

品牌：SeraCare 

Details

Non-invasive prenatal testing (NIPT) continues to expand globally and given the clinical implications, it is extremely 

critical that NIPT assays report back presence or absence of aneuploidies in an accurate and consistent manner. 

Matched maternal-fetal reference materials derived from pregnant maternal plasma enable accurate assessment of 

a broad range of NIPT assays, including those based on counting methods, SNPs, as well as differences in the length 

of maternal and fetal cfDNA. 

The Seraseq Trisomy 18 Female-Matched Reference Material can be used to develop a new test, validate an assay, 

monitor routine performance, troubleshoot problems across the entire workflow and ensure overall proficiency with 

the same sustainable product. 

Matched (or related) maternal-fetal Trisomy 18 (Edwards Syndrome) female sample compatible with a broad range 

of NIPT assay methods 

Proprietary method maintains native cfDNA size profile of ~170 bp size distribution and natural maternal-fetal size 

difference 

Offered in a plasma format capable of assessing the entire workflow from extraction through analysis (similar to 

clinical samples) 

Fetal fraction levels confirmed to be moderate to high positive to help establish initial baseline (can be customized 

to lower levels) 

Manufactured in GMP-compliant and ISO 13485-certified facilities

维百奥生物代理SeraCare对照及参比物质。

维百奥（北京）生物科技有限公司，自2018年与SeraCare（现隶属于LGC Clinical Diagnostics）合作以来，长期为中国客户

提供包括SeraSeq系列参比物质，领域包括肿瘤、生殖健康和遗传病。SeraCare研发和生产一系列临床参比物质，可以用于任何

研发阶段，以确保临床基因组学检测结果的准确性。

SeraCare参比物质涵盖的范围：

1）Next Generation Sequencing

2）Sanger Sequencing

3）Real-time PCR and digital PCR (dPCR)

4）Microarray

主要特点

1）Ready-to-use reference materials covering clinically-relevant variants and all variant types - SNVs, INDELS, CNVs, 

and RNA fusions

2）Highly multiplexed - provide significantly more data per NGS run, saving sequencing costs

3）Available in multiple formats to suite different workflow needs - purified DNA & RNA, ctDNA, encapsulated ctDNA 

in plasma, and FFPE

4）Manufactured in cGMP-compliant, ISO 13485-certified facilities

5）Stringent product release testing - all variants qualified by dPCR for allele frequencies or copy numbers