【产品概况】
产品名称:Human ALX Antibody (Tilvestamab, Research Use)
产品编号:NBR-0002
针对靶点:AXL
抗体药商品名:Tilvestamab
抗体药描述:Tilvestamab (BGB149) is a first-in-class, fully humanized, therapeutic anti-AXL function-blocking monoclonal antibody, discovered and developed by BerGenBio. A Phase Ia study in healthy volunteers has been completed.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: AXL
Synonyms: ARK; JTK11; Tyro7; UFO
Target Description: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factor GAS6 and which is thus regulating many physiological processes including cell survival, cell proliferation, migration and differentiation.
Ensembl: ENSG00000167601
Uniprot: P30530