【产品概况】
产品名称:Human CTLA-4 Antibody (Ipilimumab, Research Use)
产品编号:NBR-0025
针对靶点:CTLA-4
抗体药商品名:Ipilimumab
抗体药描述:Ipilimumab, sold under the brand name Yervoy, is a monoclonal antibody medication that works to activate the immune system by targeting CTLA-4, a protein receptor that downregulates the immune system.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: CTLA-4
Synonyms: CTLA4; CTLA-4; CD152; GSE
Target Description: nhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
Ensembl: ENSG00000163599
Uniprot: P16410