【产品概况】
产品名称:Human DR5 / TRAILR2 Antibody (Conatumumab, Research Use)
产品编号:NBR-0032
针对靶点:DR5 / TRAILR2
抗体药商品名:Conatumumab
抗体药描述:Conatumumab (originally AMG-655) is a monoclonal antibody developed for the treatment of cancer. It is a fully human monoclonal agonist antibody directed against the extracellular domain of human TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) receptor 2 (TR-2, death receptor 5) with potential antineoplastic activity.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: DR5
Synonyms: TRAILR2; KILLER; DR5; TRICK2A; TRICKB; CD262
Target Description: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor.
Ensembl: ENSG00000120889
Uniprot: O14763