【产品概况】
产品名称:Human FGFR2 Antibody (Aprutumab, Research Use)
产品编号:NBR-0039
针对靶点:FGFR2
抗体药商品名:Aprutumab
抗体药描述:Aprutumab ixadotin is the first antibody-drug conjugate (ADC) to target FGFR2 and the first to use a novel auristatin-based payload.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: FGFR2
Synonyms: K-SAM; CD332; CEK3; TK14; TK25; ECT1; KGFR; BEK; CFD1
Target Description: FGFR2 (Fibroblast Growth Factor Receptor 2) is a Protein Coding gene. Diseases associated with FGFR2 include Pfeiffer Syndrome and Crouzon Syndrome. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and GPCR Pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and protein kinase activity. An important paralog of this gene is FGFR1.
Ensembl: ENSG00000066468
Uniprot: P21802