【产品概况】
产品名称:Human HER2 Antibody (Trastuzumab, Research Use)
产品编号:NBR-0045
针对靶点:HER2
抗体药商品名:Trastuzumab
抗体药描述:Trastuzumab, sold under the brand name Herceptin among others, is a monoclonal antibody used to treat breast cancer and stomach cancer. It is specifically used for cancer that is HER2 receptor positive.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: HER2
Synonyms: ERBB2; HER2; HER-2; CD340; NGL
Target Description: ERBB2 (Erb-B2 Receptor Tyrosine Kinase 2) is a Protein Coding gene. Diseases associated with ERBB2 include Visceral Neuropathy, Familial, 2, Autosomal Recessive and Glioma Susceptibility 1. Among its related pathways are Resistance of ERBB2 KD mutants to afatinib and Signaling by ERBB2 KD Mutants. Gene Ontology (GO) annotations related to this gene include identical protein binding and protein kinase activity. An important paralog of this gene is EGFR.
Ensembl: ENSG00000141736
Uniprot: P04626