【产品概况】
产品名称:Human IL-17RA Antibody (Brodalumab, Research Use)
产品编号:NBR-0048
针对靶点:IL-17RA
抗体药商品名:Brodalumab
抗体药描述:Brodalumab, sold under the brand name Siliq in the US and Kyntheum in the EU, is a human monoclonal antibody designed for the treatment of inflammatory diseases.n February 2017, it received US FDA approval to treat moderate to severe plaque psoriasis in people who have not improved with other treatments.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: IL-17RA
Synonyms: IL-17RA; CDw217; HIL-17R; CD217; IL17R
Target Description: IL17RA (Interleukin 17 Receptor A) is a Protein Coding gene. Diseases associated with IL17RA include Immunodeficiency 51 and Chronic Mucocutaneous Candidiasis. Among its related pathways are SARS-CoV-2 Infection and IL-17 Family Signaling Pathways. Gene Ontology (GO) annotations related to this gene include interleukin-17 receptor activity. An important paralog of this gene is IL17RD.
Ensembl: ENSG00000177663
Uniprot: Q96F46