【产品概况】
产品名称:Human IL-6R Antibody (Sarilumab, Research Use)
产品编号:NBR-0054
针对靶点:IL-6R
抗体药商品名:Sarilumab
抗体药描述:Sarilumab, sold under the brand name Kevzara, is a human monoclonal antibody medication against the interleukin-6 receptor. Regeneron Pharmaceuticals and Sanofi developed the drug for the treatment of rheumatoid arthritis (RA), for which it received US FDA approval on 22 May 2017 and European Medicines Agency approval on 23 June 2017.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: IL-6R
Synonyms: Gp80; IL-1Ra; CD126; IL-6R; IL6RA
Target Description: Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal 1. Signal activation necessitate an association with IL6ST.
Ensembl: ENSG00000160712
Uniprot: P08887