【产品概况】
产品名称:Human KIR Antibody (Lirilumab, Research Use)
产品编号:NBR-0056
针对靶点:KIR
抗体药商品名:Lirilumab
抗体药描述:Lirilumab (INN) is a human monoclonal antibody designed for the treatment of cancer.[It binds to KIR2DL1/2L3.This drug was developed by Innate Pharma and is licensed to Bristol-Myers Squibb.A phase 2 clinical trial for acute myeloid leukemia (AML) was terminated early ("failed") in 2017.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: KIR
Synonyms: KIR3DL1; NKB1; CD158E1; NKB1B 2; CD158e1/2
Target Description: Receptor on natural killer (NK) cells for some HLA-C alleles such as w4 and w6. Inhibits the activity of NK cells thus preventing cell lysis.
Ensembl: ENSG00000167633
Uniprot: P43629