【产品概况】
产品名称:Human PD-1 Antibody (Spartalizumab, Research Use)
产品编号:NBR-0065
针对靶点:PD-1
抗体药商品名:Spartalizumab
抗体药描述:Spartalizumab is a monoclonal antibody and checkpoint inhibitor that is being investigated for melanoma.This drug is being developed by Novartis. As of 2018, spartalizumab is undergoing Phase III trials.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: PD-1
Synonyms: PDCD1; CD279; HSLE1; PD-1
Target Description: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self. Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2.
Ensembl: ENSG00000188389
Uniprot: Q15116