【产品概况】
产品名称:Human 4-1BB Antibody (Utomilumab, Research Use)
产品编号:NBR-0090
针对靶点:4-1BB
抗体药商品名:Utomilumab
抗体药描述:Utomilumab (PF-05082566) targets CD137 receptor to stimulate a more intense immune system attack on cancers. It is a fully human IgG2 monoclonal antibody.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: 4-1BB
Synonyms: TNFRSF9; CD137; 4-1BB; ILA
Target Description: TNFRSF9 (TNF Receptor Superfamily Member 9) is a Protein Coding gene. Diseases associated with TNFRSF9 include Relapsed/Refractory Diffuse Large B-Cell Lymphoma and Immunodeficiency 16. Among its related pathways are Akt Signaling and TNF Superfamily - Human Ligand-Receptor Interactions and their Associated Functions. Gene Ontology (GO) annotations related to this gene include signaling receptor activity and cytokine binding. An important paralog of this gene is TNFRSF21.
Ensembl: ENSG00000049249
Uniprot: Q07011