产品名称：Human 4-1BB Antibody (Urelumab, Research Use)
产品编号：NBR-0091
针对靶点：4-1BB
抗体药商品名：Urelumab
抗体药描述：Urelumab is a fully human IgG4 monoclonal antibody developed by Bristol-Myers Squibb for the treatment of cancer and solid tumors. The first phase I trial began in 2006 and final results were published in 2015. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: 4-1BB
Synonyms: TNFRSF9; CD137; 4-1BB; ILA
Target Description: TNFRSF9 (TNF Receptor Superfamily Member 9) is a Protein Coding gene. Diseases associated with TNFRSF9 include Relapsed/Refractory Diffuse Large B-Cell Lymphoma and Immunodeficiency 16. Among its related pathways are Akt Signaling and TNF Superfamily - Human Ligand-Receptor Interactions and their Associated Functions. Gene Ontology (GO) annotations related to this gene include signaling receptor activity and cytokine binding. An important paralog of this gene is TNFRSF21.
Ensembl:  ENSG00000049249
Uniprot:  Q07011