【产品概况】
产品名称:Human ACVR2B Antibody (Bimagrumab, Research Use)
产品编号:NBR-0095
针对靶点:ACVR2B
抗体药商品名:Bimagrumab
抗体药描述:Bimagrumab (BYM338) is a human monoclonal antibody developed by Novartis to treat pathological muscle loss and weakness. On August 20, 2013, it was announced that bimagrumab had received a breakthrough therapy designation for sporadic inclusion body myositis (sIBM) by the US Food and Drug Administration.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: ACVR2B
Synonyms: ActR-IIB
Target Description: Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c).
Ensembl: ENSG00000114739
Uniprot: Q13705