【产品概况】
产品名称:Human ALCAM Antibody (Praluzatamab, Research Use)
产品编号:NBR-0096
针对靶点:ALCAM
抗体药商品名:Praluzatamab
抗体药描述:Praluzatamab ravtansine (CX-2009) is a conditionally activated Probody drug conjugate (PDC) comprising an anti-CD166 mAb conjugated to DM4, with a protease-cleavable linker and a peptide mask that limits target engagement in normal tissue and circulation.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: ALCAM
Synonyms: MEMD; CD166
Target Description: ALCAM (Activated Leukocyte Cell Adhesion Molecule) is a Protein Coding gene. Diseases associated with ALCAM include Stork Bite and Melanoma. Among its related pathways are Nervous system development and L1CAM interactions. Gene Ontology (GO) annotations related to this gene include signaling receptor binding. An important paralog of this gene is BCAM.
Ensembl: ENSG00000170017
Uniprot: Q13740