【产品概况】
产品名称:Human BAFF Antibody (Belimumab, Research Use)
产品编号:NBR-0108
针对靶点:BAFF
抗体药商品名:Belimumab
抗体药描述:Belimumab, sold under the brand name Benlysta, is a human monoclonal antibody that inhibits B-cell activating factor (BAFF), also known as B-lymphocyte stimulator (BLyS). It is approved in the United States, Canada, and the European Union to treat systemic lupus erythematosus (SLE).
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: BAFF
Synonyms: TNFSF13B; TALL-1; TALL1; BAFF; BLYS; B-Cell-Activating Factor; TNFSF20; THANK; CD257
Target Description: TNFSF13B (TNF Superfamily Member 13b) is a Protein Coding gene. Diseases associated with TNFSF13B include Sjogren Syndrome and Autoimmune Disease. Among its related pathways are MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and tumor necrosis factor receptor binding. An important paralog of this gene is TNFSF13.
Ensembl: ENSG00000102524
Uniprot: Q9Y275