【产品概况】
产品名称:Human Beta-Klotho Antibody (RG7992, Research Use)
产品编号:NBR-0110
针对靶点:Beta-Klotho
抗体药商品名:RG7992
抗体药描述:RG7992 (BFKB8488A) targets fibroblast growth factor receptor 1 (FGFR1) and coreceptor β klotho (KLB).
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: Beta-Klotho
Synonyms: KLB; BetaKlotho; B-Klotho; BKL
Target Description: KLB (Klotho Beta) is a Protein Coding gene. Diseases associated with KLB include Functional Diarrhea and Epilepsy, Idiopathic Generalized 4. Among its related pathways are Insulin receptor signalling cascade and Downstream signaling of activated FGFR2. Gene Ontology (GO) annotations related to this gene include hydrolase activity, hydrolyzing O-glycosyl compounds and fibroblast growth factor binding. An important paralog of this gene is KL.
Ensembl: ENSG00000134962
Uniprot: Q86Z14