【产品概况】
产品名称:Human CAIX Antibody (Girentuximab, Research Use)
产品编号:NBR-0116
针对靶点:CAIX
抗体药商品名:Girentuximab
抗体药描述:Girentuximab (trade name Rencarex) is a chimeric IgG1 monoclonal antibody to carbonic anhydrase IX (CAIX). CAIX is expressed on the surface of most renal cancer cells and is hypothesized to be on the surface of other tumor cells. It is investigational agent in clinical trials for renal cell carcinoma.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: CAIX
Synonyms: CA9
Target Description: CA9 (Carbonic Anhydrase 9) is a Protein Coding gene. Diseases associated with CA9 include Oncocytoma and Gum Cancer. Among its related pathways are Cellular responses to stimuli and Regulation of activated PAK-2p34 by proteasome mediated degradation. Gene Ontology (GO) annotations related to this gene include carbonate dehydratase activity. An important paralog of this gene is CA14.
Ensembl: ENSG00000107159
Uniprot: Q16790