产品名称：Human CD117 Antibody (LOP628, Research Use)
产品编号：NBR-0122
针对靶点：CD117
抗体药商品名：LOP628
抗体药描述：LOP628 is an antibody-drug conjugate (ADC) consisting of an anti-cKit humanized IgG1/κ antibody conjugated to a maytansine payload via a non-cleavable linker. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: CD117
Synonyms: KIT; SCFR; C-Kit; PBT
Target Description: KIT (KIT Proto-Oncogene, Receptor Tyrosine Kinase) is a Protein Coding gene. Diseases associated with KIT include Piebald Trait and Gastrointestinal Stromal Tumor. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and Regorafenib-resistant KIT mutants. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and protein kinase activity. An important paralog of this gene is CSF1R.
Ensembl: ENSG00000157404
Uniprot: P10721